Impact of sintilimab plus anlotinib on progression-free survival in advanced unresectable hepatocellular carcinoma

doi:10.4251/wjgo.v18.i8.119966

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World Journal of Gastrointestinal Oncology

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1948-5204

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Retrospective Cohort Study

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World J Gastrointest Oncol. Aug 15, 2026; 18(8): 119966
Published online Aug 15, 2026. doi: 10.4251/wjgo.v18.i8.119966

Table 4 Comparison of changes in tumor markers before and after treatment in the two groups of patients (mean ± SD)

Tumor markers	Group	Before treatment	After treatment	Difference before and after treatment	t	P value
AFP (ng/mL)	Experimental group (n = 45)	386.5 ± 124.3	128.7 ± 49.5	257.8 ± 86.4	8.895	< 0.001
AFP (ng/mL)	Control group (n = 45)	392.7 ± 118.9	219.4 ± 78.6	173.3 ± 67.2
CA19-9 (U/mL)	Experimental group (n = 45)	89.6 ± 32.4	32.8 ± 15.7	56.8 ± 21.3	7.052	< 0.001
CA19-9 (U/mL)	Control group (n = 45)	92.3 ± 30.7	57.9 ± 22.4	34.4 ± 18.5

Compared with this group before treatment, all P < 0.05. AFP: Alpha-fetoprotein; CA19-9: Carbohydrate antigen 19-9.

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Citation: Sheng C, Li H. Impact of sintilimab plus anlotinib on progression-free survival in advanced unresectable hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(8): 119966
URL: https://www.wjgnet.com/1948-5204/full/v18/i8/119966.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i8.119966

Sheng C, Li H. Impact of sintilimab plus anlotinib on progression-free survival in advanced unresectable hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(8): 119966 [DOI: 10.4251/wjgo.v18.i8.119966]

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