TCHP regulates the proliferation and apoptosis of gastric cancer cells via AKT/BCL2 signaling pathway

Figure 2 TCHP knockdown suppresses gastric cancer cell proliferation by inducing G1 phase cell cycle arrest and apoptosis. A: Effect of TCHP knockdown on cell proliferation was assessed by Ki67 immunofluorescence staining; B: Analysis by flow cytometry showed that TCHP knockdown induced G1 phase cell cycle arrest in AGS and HGC-27 cells; C: Apoptosis in AGS and HGC-27 cells following TCHP knockdown was analyzed using flow cytometry. Data are presented as mean ± SD based on three independent experiments. ^bP < 0.01; ^cP < 0.001. NC: Negative control.