Chinese herbal medicine for colorectal cancer: An overview of systematic reviews and evidence map

doi:10.4251/wjgo.120031

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Jul 15, 2026; 18(7): 120031
Published online Jul 15, 2026. doi: 10.4251/wjgo.120031

Table 2 Summary of findings of evidence in adjuvant chemotherapy combined with Chinese herbal medicine

Ref.	Patients details	Numbers of RCTs	Participants		Effect estimates	Quality of evidence
Ref.	Patients details	Numbers of RCTs	Treatment	Control	Effect estimates	Quality of evidence
1-year RFS rate
Tang et al[31]	Postoperative CRC	11	509	486	RR = 0.39, 95%CI: 0.27-0.57	Low¹^,²
2-year RFS rate
Tang et al[31]	Postoperative CRC	8	411	399	RR = 0.40, 95%CI: 0.29-0.54	Low¹^,²
3-year RFS rate
Tang et al[31]	Postoperative CRC	9	645	643	RR = 0.52, 95%CI: 0.43-0.61	Low¹^,²
Performance status (KPS improvement rate)
Zhao et al[34]	Postoperative CRC	12	368	367	RR = 0.36, 95%CI: 0.26-0.51	Low¹^,²

¹Risk of bias of included trials.

²Clinical heterogeneity.

CHM: Chinese herbal medicine; RCT: Randomized controlled trial; RFS: Relapse-free survival; KPS: Karnofsky Performance Status; CRC: Colorectal cancer; RR: Risk ratio; CI: Confidence interval.

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Citation: Wang HP, Qin XY, Xu BW, Lu TC, Gao RK, Lin M, Li J. Chinese herbal medicine for colorectal cancer: An overview of systematic reviews and evidence map. World J Gastrointest Oncol 2026; 18(7): 120031
URL: https://www.wjgnet.com/1948-5204/full/v18/i7/120031.htm
DOI: https://dx.doi.org/10.4251/wjgo.120031

Wang HP, Qin XY, Xu BW, Lu TC, Gao RK, Lin M, Li J. Chinese herbal medicine for colorectal cancer: An overview of systematic reviews and evidence map. World J Gastrointest Oncol 2026; 18(7): 120031 [DOI: 10.4251/wjgo.120031]

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