Impact of anxiety and depression on quality of life in gastric cancer patients receiving SOX neoadjuvant chemotherapy

doi:10.4251/wjgo.119170

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Jul 15, 2026; 18(7): 119170
Published online Jul 15, 2026. doi: 10.4251/wjgo.119170

Table 4 Association between anxiety and depression and adverse reactions during chemotherapy, n (%)

Symptoms	Group	Normal group (n = 80)	Anxiety-depression group (n = 73)	Statistic	P value
Gastrointestinal reactions	0	13 (16.25)	4 (5.48)	7.69	0.021
	I/II	60 (75.00)	54 (73.97)
	III-IV	7 (8.75)	15 (20.55)
Myelosuppression	0	14 (17.50)	7 (9.59)	3.49	0.175
	I/II	62 (77.50)	58 (79.45)
	III-IV	4 (5.00)	8 (10.96)
Hematological toxicity	0	16 (20.00)	11 (15.07)	1.94	0.380
	I/II	58 (72.50)	52 (71.23)
	III-IV	6 (7.50)	10 (13.70)
Neurotoxicity	0	19 (23.75)	9 (12.33)	4.49	0.106
	I/II	53 (66.25)	51 (69.86)
	III-IV	8 (10.00)	13 (17.81)

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Citation: Cui BY, Zhang Z. Impact of anxiety and depression on quality of life in gastric cancer patients receiving SOX neoadjuvant chemotherapy. World J Gastrointest Oncol 2026; 18(7): 119170
URL: https://www.wjgnet.com/1948-5204/full/v18/i7/119170.htm
DOI: https://dx.doi.org/10.4251/wjgo.119170

Cui BY, Zhang Z. Impact of anxiety and depression on quality of life in gastric cancer patients receiving SOX neoadjuvant chemotherapy. World J Gastrointest Oncol 2026; 18(7): 119170 [DOI: 10.4251/wjgo.119170]

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