Comparative analysis of curative efficacy and prognostic factors across treatment modalities for early-stage hepatocellular carcinoma (BCLC 0/A)

Table 1 General clinical characteristics of patients with Barcelona Clinic Liver Cancer stage 0/A hepatocellular carcinoma

Variables		LR	RFA	Combined	χ2	P value
Age (year)	≤ 60	24	27	22	1.498	0.473
	> 60	6	13	10
Gender	Male	21	35	21	5.29	0.071
	Female	9	5	11
LC	No	5	12	9	1.775	0.412
	Yes	25	28	23
HBV infection	No	6	6	11	3.979	0.137
	Yes	24	34	21
AFP (μg/L)	≤ 400	25	35	26	0.556	0.757
	> 400	5	5	6
PS score	0	14	40	15	31.484	0.96
	1	13	0	14
	2	3	0	3
Child-Pugh classification	A	27	35	28	0.128	0.938
	B	3	5	4
Number of tumor	1	28	36	30	0.427	0.808
	2	2	4	2
Diameter of tumor (cm)	≤ 2	12	20	14	0.727	0.695
	2-3	18	20	18
BCLC	0	12	18	13	0.221	0.896
	A	18	22	19
TBIL (μmol/L)	≤ 22	30	38	32	3.162	0.206
	> 22	0	2	0
ALB (g/L)	≥ 35	30	39	30	2.164	0.339
	< 35	0	1	2
ALT (U/L)	≤ 50	20	10	28	3.068	0.080
	> 50	10	30	4
AST (U/L)	≤ 59	29	39	32	0.994	0.608
	> 59	1	1	0
GGT (U/L)	≤ 73	28	40	32	4.896	0.086
	> 73	2	0	0
ICG-R15 (%)	≤ 10	29	40	31	1.32	0.517
	> 10	1	0	1
PLT (× 109/L)	≥ 100	28	40	31	2.674	0.263
	< 100	2	0	1

LR: Liver resection; RFA: Radiofrequency ablation; BCLC: Barcelona Clinic Liver Cancer; LC: Liver cirrhosis; HBV: Hepatitis B virus; AFP: Alpha fetoprotein; PS: Performance status; TBIL: Total bilirubin; ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transferase; ICG-R15: Indocyanine green retention rate at 15 minutes; PLT: Platelet count.