ST2, PIVKA-II, CEA, CA125 and their combinations in elderly liver metastases cancers: Development of a diagnostic scoring model

doi:10.4251/wjgo.v18.i7.118940

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Jul 15, 2026; 18(7): 118940
Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118940

Table 5 Positive rates of different combinations of soluble growth-stimulating gene 2, protein Induced by vitamin K absence or antagonist-II, carcinoembryonic antigen, and carbohydrate antigen 125, n (%)

Project portfolio	Liver metastasis group (n = 84)	Liver metastasis-free group (n = 252)
ST2 + PIVKA-II	35 (41.67)	5 (1.98)
ST2 + CEA	40 (47.62)	7 (2.78)
ST2 + CA125	45 (53.57)	5 (1.98)
PIVKA-II + CEA	42 (50.00)	5 (1.98)
PIVKA-II + CA125	43 (51.19)	6 (2.38)
CEA + CA125	41 (48.81)	6 (2.38)
ST2 + PIVKA-II + CEA	39 (46.43)	4 (1.59)
ST2 + PIVKA-II + CA125	37 (44.05)	5 (1.98)
ST2 + CEA + CA125	36 (42.86)	4 (1.59)
PIVKA-II + CEA + CA125	42 (50.00)	2 (0.79)
ST2 + PIVKA-II + CEA + CA125	47 (55.95)	2 (0.79)

ST2: Soluble growth-stimulating gene 2; PIVKA-II: Protein induced by vitamin K absence or antagonist-II; CEA: Carcinoembryonic antigen; CA125: Carbohydrate antigen 125.

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Citation: Cheng Y, Sun YS, He YM. ST2, PIVKA-II, CEA, CA125 and their combinations in elderly liver metastases cancers: Development of a diagnostic scoring model. World J Gastrointest Oncol 2026; 18(7): 118940
URL: https://www.wjgnet.com/1948-5204/full/v18/i7/118940.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i7.118940

Cheng Y, Sun YS, He YM. ST2, PIVKA-II, CEA, CA125 and their combinations in elderly liver metastases cancers: Development of a diagnostic scoring model. World J Gastrointest Oncol 2026; 18(7): 118940 [DOI: 10.4251/wjgo.v18.i7.118940]

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