ST2, PIVKA-II, CEA, CA125 and their combinations in elderly liver metastases cancers: Development of a diagnostic scoring model

doi:10.4251/wjgo.v18.i7.118940

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World Journal of Gastrointestinal Oncology

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1948-5204

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World J Gastrointest Oncol. Jul 15, 2026; 18(7): 118940
Published online Jul 15, 2026. doi: 10.4251/wjgo.v18.i7.118940

Table 4 Multivariate analysis of liver metastasis in patients in the construct group

Variable	Regression coefficient	SE	*Wald*	P value	OR value	95%CI
ST2	1.254	0.310	16.333	< 0.001	3.503	1.958-6.630
PIVKA-II	1.829	0.354	26.694	< 0.001	6.220	2.951-9.169
CEA	1.311	0.291	20.287	< 0.001	3.708	2.096-6.559
CA125	1.570	0.337	17.341	< 0.001	4.808	2.312-10.054
Fatty liver	0.765	0.283	7.287	0.007	2.148	1.233-3.743

CI: Confidence interval; OR: Odds ratio; ST2: Soluble growth-stimulating gene 2; PIVKA-II: Protein induced by vitamin K absence or antagonist-II; CEA: Carcinoembryonic antigen; CA125: Carbohydrate antigen 125.

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Citation: Cheng Y, Sun YS, He YM. ST2, PIVKA-II, CEA, CA125 and their combinations in elderly liver metastases cancers: Development of a diagnostic scoring model. World J Gastrointest Oncol 2026; 18(7): 118940
URL: https://www.wjgnet.com/1948-5204/full/v18/i7/118940.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i7.118940

Cheng Y, Sun YS, He YM. ST2, PIVKA-II, CEA, CA125 and their combinations in elderly liver metastases cancers: Development of a diagnostic scoring model. World J Gastrointest Oncol 2026; 18(7): 118940 [DOI: 10.4251/wjgo.v18.i7.118940]

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