Hsa_circ_0003848 promotes gastric cancer via miR-144-3p/mesenchymal-epithelial transition factor and serves as a plasma biomarker in Helicobacter pylori infection

Figure 1 Identification and basic features of hsa_circ_0003848 in gastric cancer. A: Venn diagram showing overlapping differentially expressed circular RNAs across datasets; B: Schematic of hsa_circ_0003848 derived from exons 2-3 of PSEN1; C: Sanger sequencing confirming the back-splice junction; D: Real-time quantitative PCR using random and oligo (dT) primers showing the circular nature of hsa_circ_0003848; E: RNA stability assay indicating that hsa_circ_0003848 is more stable than linear PSEN1; F: Subcellular localization showing cytoplasmic enrichment of hsa_circ_0003848. n = 3.