Tumor-related imaging parameters predict response and survival after neoadjuvant chemoradiotherapy in rectal cancer

Table 5 Univariate analysis of prognostic variables for overall survival

Variables	Univariate analysis			Multivariate analysis
	HR	95%CI	P value	HR	95%CI	P value
Age	1.019	0.983-1.056	0.312
Maximum diameter of the tumor	1.015	0.983-1.049	0.365
Length	1.009	0.991-1.028	0.317
Short diameter of the largest lymph node	1.013	0.950-1.081	0.696
Maximum diameter perpendicular to the intestinal wall on T2WI	0.997	0.952-1.044	0.89
Maximum cross-sectional area of the tumor on T2WI	1.000	0.999-1.000	0.952
Distance of the tumor from the anal verge	1.001	0.989-1.014	0.832
Carcinoembryonic antigen	0.999	0.993-1.004	0.566
Carbohydrate antigen 19-9	1.000	0.998-1.002	0.938
Body mass index	0.990	0.877-1.117	0.871
Sex	0.697	0.297-1.632	0.406
Circle	1.120	0.632-1.989	0.696
Signal	2.046	0.931-4.499	0.075
Spiculation	1.008	0.480-2.114	0.984
Node	2.655	1.281-5.503	0.009	2.199	0.965-5.014	0.061
Stratification	0.918	0.425-1.983	0.828
MRF status	2.149	1.005-4.596	0.049	1.5013	0.636-3.543	0.354
Extramural vascular invasion status	1.955	0.900-4.245	0.090
ExtraMRF	1.936	0.931-4.029	0.077
Clinical T stage	1.797	0.865-3.734	0.116
Clinical N stage	1.592	0.993-2.552	0.053
Sarcopenia	1.269	0.577-2.790	0.554

HR: Hazard ratio; MRF: Mesorectal fascia; T2WI: T2-weighted imaging.