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Retrospective Study
Copyright: ©Author(s) 2026.
World J Gastrointest Oncol. Jun 15, 2026; 18(6): 117582
Published online Jun 15, 2026. doi: 10.4251/wjgo.v18.i6.117582
Table 6 Comparison of features between the training and validation sets, mean ± SD/n (%)
Variables
Total (n = 200)
Test (n = 60)
Train (n = 140)
Statistic
P value
Neutrophil3.91 ± 2.324.21 ± 3.063.78 ± 1.92t = 1.000.320
Lymphocyte1.38 ± 0.591.40 ± 0.691.37 ± 0.54t = 0.350.724
PD-L1 expressionχ2 = 0.120.732
CPS < 587 (43.50)25 (41.67)62 (44.29)
CPS ≥ 5113 (56.50)35 (58.33)78 (55.71)
MMR statusχ2 = 1.200.274
pMMR168 (84.00)53 (88.33)115 (82.14)
dMMR32 (16.00)7 (11.67)25 (17.86)
CARχ2 = 0.001.000
High80 (40.00)24 (40.00)56 (40.00)
Low120 (60.00)36 (60.00)84 (60.00)
Sexχ2 = 0.630.426
Female75 (37.50)20 (33.33)55 (39.29)
Male125 (62.50)40 (66.67)85 (60.71)
Ageχ2 = 0.580.448
< 60 years78 (39.00)21 (35.00)57 (40.71)
≥ 60 years122 (61.00)39 (65.00)83 (59.29)
BMIχ2 = 1.730.189
< 25166 (83.00)53 (88.33)113 (80.71)
≥ 2534 (17.00)7 (11.67)27 (19.29)
CEAχ2 = 0.010.925
< 379 (39.50)24 (40.00)55 (39.29)
≥ 3121 (60.50)36 (60.00)85 (60.71)
CA199χ2 = 2.760.097
< 37126 (63.00)43 (71.67)83 (59.29)
≥ 3774 (37.00)17 (28.33)57 (40.71)
ECOG PSχ2 = 0.700.403
072 (36.00)19 (31.67)53 (37.86)
1128 (64.00)41 (68.33)87 (62.14)
Stagingχ2 = 0.160.687
III91 (45.50)26 (43.33)65 (46.43)
IV109 (54.50)34 (56.67)75 (53.57)
Differentiationχ2 = 0.260.607
Poorly/undifferentiated180 (90.00)55 (91.67)125 (89.29)
Medium/high20 (10.00)5 (8.33)15 (10.71)
Siteχ2 = 0.040.838
Gastric and esophageal binding58 (29.00)18 (30.00)40 (28.57)
Stomach142 (71.00)42 (70.00)100 (71.43)
Peritoneal metastasisχ2 = 0.170.679
No157 (78.50)46 (76.67)111 (79.29)
Yes43 (21.50)14 (23.33)29 (20.71)
Liver metastasisχ2 = 0.200.655
No156 (78.00)48 (80.00)108 (77.14)
Yes44 (22.00)12 (20.00)32 (22.86)
EBV statusχ2 = 0.060.802
No-infect187 (93.50)57 (95.00)130 (92.86)
infect13 (6.50)3 (5.00)10 (7.14)


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