Characteristics and prognosis of primary gastric adenosquamous carcinoma: A multicenter retrospective study based on propensity score matching

doi:10.4251/wjgo.v18.i5.117580

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. May 15, 2026; 18(5): 117580
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.117580

Table 3 Characteristics of patients with primary gastric adenosquamous carcinoma and gastric adenocarcinoma before and after propensity score matching

Characteristics	Before PSM			After PSM
Characteristics	GAC (n = 468)	PGASC¹ (n = 89)	P value	GAC (n = 77)	PGASC (n = 77)	P value
Age, years (≤ 60/> 60)	163/305	31/58	> 0.990	26/51	27/50	0.870
Sex (female/male)	152/316	17/72	0.010	19/58	17/60	0.700
Surgical resection (incomplete resection/complete resection)	275/193	58/31	0.260	44/33	46/31	0.740
Primary site (non-cardia/cardia)	361/107	52/37	< 0.001	49/28	43/34	0.320
pT stage² (pT1/pT2/pT3/pT4)	79/51/31/307	2/5/21/61	< 0.001	2/3/7/65	2/5/19/51	0.050
pN stage² (pN0/pN1/pN2/pN3)	163/76/99/130	16/20/22/31	0.020	19/12/12/34	16/20/16/25	0.240
pM stage² (pM0/pM1)	434/34	76/13	0.020	64/13	65/12	0.830
Chemotherapy (no/yes)	155/313	39/50	0.050	29/48	28/49	0.870

¹This cohort of patients with primary gastric adenosquamous carcinoma included the patients with available overall survival data.

²Based on the American Joint Committee on Cancer (8^th edition) staging system.

GAC: Gastric adenocarcinoma; PGASC: Primary gastric adenosquamous carcinoma; pM: Pathological metastasis; pN: Pathological node; pT: Pathological tumor; PSM: Propensity score matching.

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Citation: Chen YW, Dong ZY, Wang XX, Cao Y, Lin JX, Chen H, Zhang HY, Xiao YB, Li GX, Li ZR, Chen L, Xia X, Zhang ZZ. Characteristics and prognosis of primary gastric adenosquamous carcinoma: A multicenter retrospective study based on propensity score matching. World J Gastrointest Oncol 2026; 18(5): 117580
URL: https://www.wjgnet.com/1948-5204/full/v18/i5/117580.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i5.117580

Chen YW, Dong ZY, Wang XX, Cao Y, Lin JX, Chen H, Zhang HY, Xiao YB, Li GX, Li ZR, Chen L, Xia X, Zhang ZZ. Characteristics and prognosis of primary gastric adenosquamous carcinoma: A multicenter retrospective study based on propensity score matching. World J Gastrointest Oncol 2026; 18(5): 117580 [DOI: 10.4251/wjgo.v18.i5.117580]

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