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Retrospective Cohort Study
Copyright: ©Author(s) 2026.
World J Gastrointest Oncol. May 15, 2026; 18(5): 117410
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.117410
Table 2 Demographics and clinicopathological characteristics of patients with upper gastric signet-ring cell carcinoma who underwent total gastrectomy or proximal gastrectomy after propensity score matching, n (%)
Demographic and clinical characteristicsSRCC
PG (n = 94)
TG (n = 130)
P value
SexMale52 (55.3)74 (56.9)0.939
Female42 (44.7)56 (43.1)
Age, mean (SD)57.54 (11.82)52.87 (10.68)0.115
BMI, mean (SD)23.71 (3.48)23.31 (2.96)0.601
Surgical approachLaparotomy48 (51.1)68 (52.3)0.338
Laparoscopy46 (48.9)60 (46.2)
Convert to laparotomy0 (0.0)2 (1.5)
Neoadjuvant therapyNo74 (78.7)92 (70.8)0.104
Yes20 (21.3)38 (29.2)
Size, mean (SD)2.76 (0.82)2.90 (0.91)0.118
LaurenIntestinal14 (14.9)15 (11.5)0.121
Mixed24 (25.5)30 (23.1)
Diffuse56 (59.6)85 (65.4)
BorrmannSuperficial48 (51.1)63 (48.4)0.062
Ulcerative46 (48.9)67 (51.6)
Vessel invasionNegative44 (46.8)74 (56.9)0.055
Positive50 (53.2)56 (43.1)
Nerve invasionNegative40 (42.6)50 (38.5)0.061
Positive54 (57.4)80 (61.5)
Pathological T-stageT3-464 (68.1)92 (70.8)0.772
T1-230 (31.9)38 (29.2)
Pathological N-stageNegative37 (39.3)64 (49.2)0.617
Positive57 (60.7)66 (50.8)
Pathological stageI38 (40.2)46 (35.4)0.833
II20 (21.3)26 (20.0)
III34 (36.3)54 (41.5)
IV2 (2.2)4 (3.1)


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