Copyright: ©Author(s) 2026.
World J Gastrointest Oncol. May 15, 2026; 18(5): 117410
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.117410
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.117410
Table 2 Demographics and clinicopathological characteristics of patients with upper gastric signet-ring cell carcinoma who underwent total gastrectomy or proximal gastrectomy after propensity score matching, n (%)
| Demographic and clinical characteristics | SRCC | |||
| PG (n = 94) | TG (n = 130) | P value | ||
| Sex | Male | 52 (55.3) | 74 (56.9) | 0.939 |
| Female | 42 (44.7) | 56 (43.1) | ||
| Age, mean (SD) | 57.54 (11.82) | 52.87 (10.68) | 0.115 | |
| BMI, mean (SD) | 23.71 (3.48) | 23.31 (2.96) | 0.601 | |
| Surgical approach | Laparotomy | 48 (51.1) | 68 (52.3) | 0.338 |
| Laparoscopy | 46 (48.9) | 60 (46.2) | ||
| Convert to laparotomy | 0 (0.0) | 2 (1.5) | ||
| Neoadjuvant therapy | No | 74 (78.7) | 92 (70.8) | 0.104 |
| Yes | 20 (21.3) | 38 (29.2) | ||
| Size, mean (SD) | 2.76 (0.82) | 2.90 (0.91) | 0.118 | |
| Lauren | Intestinal | 14 (14.9) | 15 (11.5) | 0.121 |
| Mixed | 24 (25.5) | 30 (23.1) | ||
| Diffuse | 56 (59.6) | 85 (65.4) | ||
| Borrmann | Superficial | 48 (51.1) | 63 (48.4) | 0.062 |
| Ulcerative | 46 (48.9) | 67 (51.6) | ||
| Vessel invasion | Negative | 44 (46.8) | 74 (56.9) | 0.055 |
| Positive | 50 (53.2) | 56 (43.1) | ||
| Nerve invasion | Negative | 40 (42.6) | 50 (38.5) | 0.061 |
| Positive | 54 (57.4) | 80 (61.5) | ||
| Pathological T-stage | T3-4 | 64 (68.1) | 92 (70.8) | 0.772 |
| T1-2 | 30 (31.9) | 38 (29.2) | ||
| Pathological N-stage | Negative | 37 (39.3) | 64 (49.2) | 0.617 |
| Positive | 57 (60.7) | 66 (50.8) | ||
| Pathological stage | I | 38 (40.2) | 46 (35.4) | 0.833 |
| II | 20 (21.3) | 26 (20.0) | ||
| III | 34 (36.3) | 54 (41.5) | ||
| IV | 2 (2.2) | 4 (3.1) | ||
- Citation: Wang SD, Chang YZ, Ding SK, Bian ZM, Xie YB. Prognosis of signet-ring cell carcinoma after proximal gastrectomy was comparable to total gastrectomy but with better nutrition status. World J Gastrointest Oncol 2026; 18(5): 117410
- URL: https://www.wjgnet.com/1948-5204/full/v18/i5/117410.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v18.i5.117410