Metastasis-associated colon cancer 1 drives pancreatic cancer via p53/Notch signaling

Figure 6 Analysis of resistance to drug based on the expression of metastasis-associated colon cancer 1. A: Analysis for the sensitivity of drug through different databases; B: Cancer Therapeutics Response Portal; C: Genomics of drug sensitivity in cancer; D: Predicting potential compounds to target metastasis-associated colon cancer 1 (MACC1). Visualized the top 5 selected compounds on the basis of analysis through connectivity map, that could potentially target MACC1; E and F: Those with high expression of MACC1 survived better; G: The expression of MACC1 was higher in the complete or partial response group; H: The proportion of complete remission or partial remission group with elevated expression of MACC1; I: The compounds with significance between high expression of MACC1 and low expression of MACC1 in Cancer Therapeutics Response Portal database.