Metastasis-associated colon cancer 1 drives pancreatic cancer via p53/Notch signaling

Figure 3 Metastasis-associated colon cancer 1 expression correlates with infiltration of immunological factors. A: The heatmap showed a prominent correlation of expression level of metastasis-associated colon cancer 1 (MACC1) with chemokine, immune-stimulatory, major histocompatibility complex genes, chemokine receptor, and immune-inhibitor; B: The Tracking Tumor Immunophenotype scores differences calculation between low expression MACC1 group and high expression MACC1 group. The correlation between MACC1 and tumor microenvironment feature scores was visualized by radar map, and the overall negative correlation trend was observed; C: Evaluation of the correlation of MACC1 expression with cancer immune infiltration seven software were used; D: Cell sources of MACC1 in pan-cancer at the single-cell level.