Impact of sintilimab with first-line therapy on tumor marker response in advanced gastric cancer

doi:10.4251/wjgo.v18.i5.117085

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. May 15, 2026; 18(5): 117085
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.117085

Table 4 Comparison of tumor reduction rate, mean (interquartile range)

Group	Tumor reduction rate
Group	Pre-treatment (V₀) (mm³)	Post-12-week (V₁) (mm³)	Tumor reduction rate (ΔV%)
Control (n = 30)	41032 (12342, 134726)	33216 (6759, 73546)	19 (5, 32)
Combination (n = 30)	40321 (13452, 123492)	13246 (4358, 43667)	67 (52, 78)
Z value	0.125	2.894	5.672
P value	0.901	0.004	< 0.001

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Citation: Quan HL, Xia L, Hu Y, Wang GY, Wang C. Impact of sintilimab with first-line therapy on tumor marker response in advanced gastric cancer. World J Gastrointest Oncol 2026; 18(5): 117085
URL: https://www.wjgnet.com/1948-5204/full/v18/i5/117085.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i5.117085

Quan HL, Xia L, Hu Y, Wang GY, Wang C. Impact of sintilimab with first-line therapy on tumor marker response in advanced gastric cancer. World J Gastrointest Oncol 2026; 18(5): 117085 [DOI: 10.4251/wjgo.v18.i5.117085]

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