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Copyright: ©Author(s) 2026.
World J Gastrointest Oncol. May 15, 2026; 18(5): 116882
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.116882
Figure 3
Figure 3 A precision diagnostic and therapeutic roadmap for human epidermal growth factor receptor 2-positive gastric cancer. This flowchart delineates the integrated clinical decision-making pathway, from initial diagnosis and molecular subtyping through the sequential selection of therapies (first- to later-line) and ongoing dynamic monitoring. NGS: Next-generation sequencing; ctDNA: Circulating tumor DNA; HER2: Human epidermal growth factor receptor 2; MET: Mesenchymal-epithelial transition factor; EGFR: Epidermal growth factor receptor; IO: Immunotherapy; ADC: Antibody-drug conjugate.


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