Comprehensive geriatric assessment guiding treatment and survival in elderly digestive tumor patients: A retrospective study

doi:10.4251/wjgo.v18.i5.116640

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. May 15, 2026; 18(5): 116640
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.116640

Table 7 Multivariate Cox regression analysis of progression-free survival in both groups

Variable	HR	95%CI	P value
Age (per five-year increase)	1.32	1.05-1.66	0.018
ECOG score (≥ 2 vs < 2)	1.87	1.24-2.82	0.003
TNM stage (stage IV vs I-III)	2.45	1.65-3.64	< 0.001
Comprehensive geriatric assessment category (ref = control group)	-	-	0.028
Fit	0.65	0.42-1.01	0.055
Vulnerable	0.71	0.50-0.99	0.046
Frail	1.05	0.62-1.78	0.856

CI: Confidence interval; HR: Hazard ratio; ECOG: Eastern Cooperative Oncology Group; TNM: Tumor-node-metastasis.

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Citation: Zhu L, Liu XF. Comprehensive geriatric assessment guiding treatment and survival in elderly digestive tumor patients: A retrospective study. World J Gastrointest Oncol 2026; 18(5): 116640
URL: https://www.wjgnet.com/1948-5204/full/v18/i5/116640.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i5.116640

Zhu L, Liu XF. Comprehensive geriatric assessment guiding treatment and survival in elderly digestive tumor patients: A retrospective study. World J Gastrointest Oncol 2026; 18(5): 116640 [DOI: 10.4251/wjgo.v18.i5.116640]

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