Protective effects of Butia capitata extract against colitis-driven colorectal tumorigenesis: Insights into its anti-inflammatory and antinociceptive activities

doi:10.4251/wjgo.v18.i5.116568

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. May 15, 2026; 18(5): 116568
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.116568

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Figure 11 Schematic of the supposed joint activity of antioxidants and chlorogenic acid from the fruit of Butia capitata on cellular targets of signaling pathways associated with colitis inflammation and DNA damage. TRP: Tryptophan; Kyn: Kynurenine; KPM: Kynurenine metabolites; AA: Arachidonic acid; S: Sphingosine; S1P: Sphingosine 1-phosphate; DHA: Dehydroascorbate; DHAR: Semidehydroascorbate reductase; GR: Glutathione reductase. ROS: Reactive oxygen species; STAT3: Signal transducer and activator of transcription 3; IDO1: Indoleamine 2,3-dioxygenase 1; IL: Interleukin; 7TM: Seven-transmembrane.

Citation: Da Silva PB, Lopes-Bute L, Fischer J, Parcianello AP, Pires-Duarte R, Luiz RM, Brandalize APC, Melo FF, Wendel CF, Teixeira KN, Zarpelon-Schutz AC. Protective effects of Butia capitata extract against colitis-driven colorectal tumorigenesis: Insights into its anti-inflammatory and antinociceptive activities. World J Gastrointest Oncol 2026; 18(5): 116568
URL: https://www.wjgnet.com/1948-5204/full/v18/i5/116568.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i5.116568

Da Silva PB, Lopes-Bute L, Fischer J, Parcianello AP, Pires-Duarte R, Luiz RM, Brandalize APC, Melo FF, Wendel CF, Teixeira KN, Zarpelon-Schutz AC. Protective effects of Butia capitata extract against colitis-driven colorectal tumorigenesis: Insights into its anti-inflammatory and antinociceptive activities. World J Gastrointest Oncol 2026; 18(5): 116568 [DOI: 10.4251/wjgo.v18.i5.116568]

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