Protective effects of Butia capitata extract against colitis-driven colorectal tumorigenesis: Insights into its anti-inflammatory and antinociceptive activities

Figure 10  Interactions of the indoleamine 2,3-dioxygenase 1/chlorogenic acid complex. A: Chemical bonds between chlorogenic acid and the amino acid residues/heme of indoleamine 2,3-dioxygenase 1 (IDO1); B: Chain A of IDO1 indicating the heme group; C: The red region indicates the binding site of chain A of IDO1. The two-dimensional diagrams show the chemical bonds between receptor amino acid residues and chlorogenic acid atoms. The internal legend indicates the type of chemical bond according to the color code. Amino acid residues are represented within spheres by the three-letter code followed by the residue position in the primary sequence. L: Ligand.