Icaritin suppresses colorectal cancer invasion and metastasis through regulation of epithelial-mesenchymal transition and the Wnt/β-catenin signaling pathway

doi:10.4251/wjgo.v18.i5.115697

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. May 15, 2026; 18(5): 115697
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.115697

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Figure 6 Effects of icaritin on colon cancer formation in vivo. Thirty-nine days after establishment of the xenograft model, all mice were sacrificed and subcutaneous tumors were dissected. A: Volume and weight of dissected tumors; B: Positive cells, characterized by brown granules in the nuclei, were identified in the immunohistochemistry assay assessing Ki67. Indexes are shown as mean ± SD (n = 5), P < 0.05 compared with the control group.

Citation: Li X, Li YJ, Ren DD, Yuan M, Qi YR, Li HW, Zhang Y, Wang RY. Icaritin suppresses colorectal cancer invasion and metastasis through regulation of epithelial-mesenchymal transition and the Wnt/β-catenin signaling pathway. World J Gastrointest Oncol 2026; 18(5): 115697
URL: https://www.wjgnet.com/1948-5204/full/v18/i5/115697.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i5.115697

Li X, Li YJ, Ren DD, Yuan M, Qi YR, Li HW, Zhang Y, Wang RY. Icaritin suppresses colorectal cancer invasion and metastasis through regulation of epithelial-mesenchymal transition and the Wnt/β-catenin signaling pathway. World J Gastrointest Oncol 2026; 18(5): 115697 [DOI: 10.4251/wjgo.v18.i5.115697]

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