Occult intestinal angiosarcoma presenting as refractory anemia during tyrosine kinase inhibitor therapy for chronic myeloid leukemia: A case report

doi:10.4251/wjgo.v18.i4.116365

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Apr 15, 2026; 18(4): 116365
Published online Apr 15, 2026. doi: 10.4251/wjgo.v18.i4.116365

Table 1 Key laboratory values before and at presentation

Parameter	May 2024 (baseline)	September 2024 to October 2024 (acute presentation)
Hemoglobin (g/dL)	13.0	5.2
MCV (fL)	86	68.7 (microcytic)
Ferritin (ng/mL)	137	26.4 (low-normal)
Reticulocytes (%)	-	1.2
White blood count (× 10⁹/L)	14.9	- (not significantly changed)
BCR-ABL1 (%)	0.0061	< 0.0030 (stable MR4.5)
Bilirubin (total/direct; mg/dL)	-	0.24/0.11
Haptoglobin (mg/dL)	-	365 (high)
Lactate dehydrogenase (U/L)	-	168
FIT	-	Negative
Vitamin B12/folate	Normal	Normal

MCV: Mean corpuscular volume; FIT: Fecal immunochemical test.

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Citation: Najdi T, Seif S, Khoury D, Kahwagi A, Wehbe P, Karam R, El Halabi L, Slim R, Chakhtoura G, Trak V, Eid R. Occult intestinal angiosarcoma presenting as refractory anemia during tyrosine kinase inhibitor therapy for chronic myeloid leukemia: A case report. World J Gastrointest Oncol 2026; 18(4): 116365
URL: https://www.wjgnet.com/1948-5204/full/v18/i4/116365.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i4.116365

Najdi T, Seif S, Khoury D, Kahwagi A, Wehbe P, Karam R, El Halabi L, Slim R, Chakhtoura G, Trak V, Eid R. Occult intestinal angiosarcoma presenting as refractory anemia during tyrosine kinase inhibitor therapy for chronic myeloid leukemia: A case report. World J Gastrointest Oncol 2026; 18(4): 116365 [DOI: 10.4251/wjgo.v18.i4.116365]

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