Clinical prediction of carcinoembryonic antigen combined with neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio for postoperative survival in colorectal cancer

doi:10.4251/wjgo.v18.i4.115687

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World Journal of Gastrointestinal Oncology

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1948-5204

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Apr 15, 2026; 18(4): 115687
Published online Apr 15, 2026. doi: 10.4251/wjgo.v18.i4.115687

Table 4 Predictive value of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and carcinoembryonic antigen

Indicator	AUC	Optimal cutoff	Youden index	Sensitivity (%)	Specificity (%)	95%CI	P value
NLR	0.896	4.01	0.7284	76.74	96.10	0.828-0.945	< 0.0001
PLR	0.805	141.14	0.7544	76.74	98.70	0.723-0.872	< 0.0001
CEA	0.880	15.49	0.6192	81.40	80.52	0.817-0.923	< 0.0001
Joint detection	0.977		0.9118	97.67	93.51	0.931-0.996	< 0.0001

NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; CEA: Carcinoembryonic antigen; AUC: Area under the curve.

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Citation: Wang T, Liu C, Jiang J. Clinical prediction of carcinoembryonic antigen combined with neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio for postoperative survival in colorectal cancer. World J Gastrointest Oncol 2026; 18(4): 115687
URL: https://www.wjgnet.com/1948-5204/full/v18/i4/115687.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i4.115687

Wang T, Liu C, Jiang J. Clinical prediction of carcinoembryonic antigen combined with neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio for postoperative survival in colorectal cancer. World J Gastrointest Oncol 2026; 18(4): 115687 [DOI: 10.4251/wjgo.v18.i4.115687]

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