Copyright: ©Author(s) 2026.
World J Gastrointest Oncol. Apr 15, 2026; 18(4): 114567
Published online Apr 15, 2026. doi: 10.4251/wjgo.v18.i4.114567
Published online Apr 15, 2026. doi: 10.4251/wjgo.v18.i4.114567
Figure 3 Crosstalk network of cellular-mesenchymal epithelial transition factor/hepatocyte growth factor pathway (partial).
VEGR: Vascular endothelial growth factor; EGFR: Epidermal growth factor receptor; HGF: Hepatocyte growth factor; c-Met: Cellular-mesenchymal epithelial transition factor; HGFLP: Hepatocyte growth factor-like protein; IGF1R: Insulin-like growth factor 1 receptors; MAPK: Mitogen-activated protein kinases; SCR: Selective catalytic reduction; FAK: Focal adhesion kinase; STAT3: Signal transducer and activator of transcription 3; PI3K: Phosphoinositide 3-kinase; AKT: Protein kinase B; APK: Activated protein kinases; RAS: Rat sarcoma; GRB2: Growth factor receptor-bound protein-2; GAB1: Growth factor receptor-bound protein-1.
- Citation: Wen JK, Xia J, Yu L, Xu GL, Ye GF, Lin YH. Could deciphering cellular-mesenchymal epithelial transition factor/hepatocyte growth factor network dynamics unlock novel biomarker-driven therapies for colorectal cancer? World J Gastrointest Oncol 2026; 18(4): 114567
- URL: https://www.wjgnet.com/1948-5204/full/v18/i4/114567.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v18.i4.114567