Could deciphering cellular-mesenchymal epithelial transition factor/hepatocyte growth factor network dynamics unlock novel biomarker-driven therapies for colorectal cancer?

doi:10.4251/wjgo.v18.i4.114567

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Apr 15, 2026; 18(4): 114567
Published online Apr 15, 2026. doi: 10.4251/wjgo.v18.i4.114567

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Figure 2 The mechanisms of cellular-mesenchymal epithelial transition factor hyperactivation. c-Met: Cellular-mesenchymal epithelial transition factor; HGF: Hepatocyte growth factor; PTPRZ1-MET: Protein tyrosine phosphatase receptor zeta 1-mesenchymal epithelial transition factor; CLIP2-MET: Containing linker protein 2-mesenchymal epithelial transition factor; TRIM4-MET: Tripartite motif containing 4- mesenchymal epithelial transition factor.

Citation: Wen JK, Xia J, Yu L, Xu GL, Ye GF, Lin YH. Could deciphering cellular-mesenchymal epithelial transition factor/hepatocyte growth factor network dynamics unlock novel biomarker-driven therapies for colorectal cancer? World J Gastrointest Oncol 2026; 18(4): 114567
URL: https://www.wjgnet.com/1948-5204/full/v18/i4/114567.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i4.114567

Wen JK, Xia J, Yu L, Xu GL, Ye GF, Lin YH. Could deciphering cellular-mesenchymal epithelial transition factor/hepatocyte growth factor network dynamics unlock novel biomarker-driven therapies for colorectal cancer? World J Gastrointest Oncol 2026; 18(4): 114567 [DOI: 10.4251/wjgo.v18.i4.114567]

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