Cost-effectiveness of sponge cytology test vs endoscopy for esophageal squamous cell carcinoma screening in high-risk areas

doi:10.4251/wjgo.v18.i3.117278

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Evidence-Based Medicine

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Mar 15, 2026; 18(3): 117278
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.117278

Table 2 Base case: Health outcomes

Strategy	Health outcomes (per 100000 participants)
Strategy	ESCC cases	ESCC deaths
No screening	3134	2409
Sponge cytology screening
Once	2962	2266
Every 10 years	2515	1874
Every 5 years	2011	1469
Every 3 years	1510	1088
Every 2 years	1060	750
Every year	373	257
Endoscopic screening
Once	2943	2305
Every 10 years	2606	2006
Every 5 years	2277	1685
Every 3 years	1867	1362
Every 2 years	1470	1052
Every year	755	514

Health outcomes are presented per 100000 participants for each screening strategy. ESCC: Esophageal squamous cell carcinoma.

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Citation: Xu YS, Gao Y, Jiao YF, Yu CT, Wang W, Wang TL, Chu C, Lin H, Xu JF, Xin L, Wang LW. Cost-effectiveness of sponge cytology test vs endoscopy for esophageal squamous cell carcinoma screening in high-risk areas. World J Gastrointest Oncol 2026; 18(3): 117278
URL: https://www.wjgnet.com/1948-5204/full/v18/i3/117278.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i3.117278

Xu YS, Gao Y, Jiao YF, Yu CT, Wang W, Wang TL, Chu C, Lin H, Xu JF, Xin L, Wang LW. Cost-effectiveness of sponge cytology test vs endoscopy for esophageal squamous cell carcinoma screening in high-risk areas. World J Gastrointest Oncol 2026; 18(3): 117278 [DOI: 10.4251/wjgo.v18.i3.117278]

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