Dual-parameter liquid biopsy using plasma miR-21-5p and T cell LAIR-1 mean fluorescence intensity for hepatocellular carcinoma diagnosis in a high-risk Egyptian cohort

Figure 3 Correlation matrix of biomarkers in the hepatocellular carcinoma cohort. Spearman’s rank correlation coefficients (ρ) among hsa-miR-21-5p, hsa-miR-155-5p, leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1)⁺ T cell % and mean fluorescence intensity (MFI), and alpha-fetoprotein (AFP) in patients with hepatocellular carcinoma (HCC) (n = 70). The color intensity and size of the circles are proportional to the strength of the correlation with blue indicating positive correlations. Statistical significance for all shown correlations was P < 0.001.