Dual-parameter liquid biopsy using plasma miR-21-5p and T cell LAIR-1 mean fluorescence intensity for hepatocellular carcinoma diagnosis in a high-risk Egyptian cohort

Figure 2 Receiver operating characteristic curves for discriminating hepatocellular carcinoma from cirrhosis. Receiver operating characteristic (ROC) curves illustrate the diagnostic performance of plasma hsa-miR-21-5p, hsa-miR-155-5p, leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1)⁺ T cell %, and LAIR-1 mean fluorescence intensity (MFI). The dashed diagonal line represents the line of no discrimination (area under the curve [AUC] = 0.5). The corresponding AUC values with 95% confidence intervals are provided in the inset. Analysis was based on 70 hepatocellular carcinoma (HCC) cases vs 60 cirrhosis cases.