Dual-parameter liquid biopsy using plasma miR-21-5p and T cell LAIR-1 mean fluorescence intensity for hepatocellular carcinoma diagnosis in a high-risk Egyptian cohort

Table 8 Multivariable logistic regression model for the diagnosis of hepatocellular carcinoma

Predictor	Odds ratio	95%CI	P value	Variance inflation factor
hsa-miR-21-5p (per unit)	1.013	0.831-1.235	0.899	4.8
hsa-miR-155-5p (per unit)	0.911	0.463-1.795	0.789	1.5
LAIR-1 MFI (per unit)	1.484	1.043-2.111	0.028	3.1
AFP (per ng/mL)	1.053	0.946-1.173	0.345	2.9

All predictors were included as continuous variables. The model was fitted to predict hepatocellular carcinoma (n = 70) vs cirrhosis (n = 60). A variance inflation factor value > 5 was considered indicative of significant multicollinearity. AFP: Α-fetoprotein; CI: Confidence interval; LAIR-1: Leukocyte-associated immunoglobulin-like receptor-1; MFI: Mean fluorescence intensity.