Dual-parameter liquid biopsy using plasma miR-21-5p and T cell LAIR-1 mean fluorescence intensity for hepatocellular carcinoma diagnosis in a high-risk Egyptian cohort

doi:10.4251/wjgo.v18.i3.116567

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 3

This Article

(35)

(38)

(0)

(14)

(1)

(680)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Oncology

ISSN

1948-5204

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Mar 15, 2026; 18(3): 116567
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.116567

Table 3 Biomarker levels stratified by Barcelona Clinic Liver Cancer stage in the hepatocellular carcinoma cohort

Biomarker	BCLC stage 0/A (early) (n = 38)	BCLC stage B/C (advanced) (n = 32)	P value
hsa-miR-21-5p	28.4 (25.8-34.1)	39.2 (31.5-48.9)	0.021
LAIR-1 MFI	39.8 (36.2-44.3)	46.5 (41.8-50.1)	0.007

P values were calculated using the Mann-Whitney U test. Values are presented as median (interquartile range). BCLC: Barcelona Clinic Liver Cancer; LAIR-1: Leukocyte-associated immunoglobulin-like receptor-1; MFI: Mean fluorescence intensity.

Full Size Table

Citation: Sherief DE, Shehata HH, Nosair N, Othman AAA, Sadaka E, Elgamal R. Dual-parameter liquid biopsy using plasma miR-21-5p and T cell LAIR-1 mean fluorescence intensity for hepatocellular carcinoma diagnosis in a high-risk Egyptian cohort. World J Gastrointest Oncol 2026; 18(3): 116567
URL: https://www.wjgnet.com/1948-5204/full/v18/i3/116567.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i3.116567

Sherief DE, Shehata HH, Nosair N, Othman AAA, Sadaka E, Elgamal R. Dual-parameter liquid biopsy using plasma miR-21-5p and T cell LAIR-1 mean fluorescence intensity for hepatocellular carcinoma diagnosis in a high-risk Egyptian cohort. World J Gastrointest Oncol 2026; 18(3): 116567 [DOI: 10.4251/wjgo.v18.i3.116567]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.