Clinical and endoscopic characteristics of early gastric signet ring cell carcinoma based on Helicobacter pylori infection status

Table 2 Endoscopic characteristics of patients with early gastric signet ring cell carcinoma based on Helicobacter pylori infection status, n (%)

Variables	Overall	H. pylori-positive	H. pylori-eradicated	H. pylori-uninfected	P value
n	29	12 (41.4)	7 (24.1)	10 (34.5)
Tumor size/mm (mean ± SD)	12.69 ± 5.04	13.2 ± 5.41	11.58 ± 4.57	13.47 ± 5.51	0.72
Tumor location					0.235
Gastric body	24 (82.8)	8 (66.7)	7 (100.0)	9 (90.0)
Upper third	7 (29.2)	3 (37.5)	3 (42.9)	1 (11.1)
Middle third	0	0	0	0
Lower third	17 (70.8)	5 (62.5)	4 (57.1)	8 (88.9)
Antrum	5 (17.2)	4 (33.3)	0	1 (10.0)
Morphology					0.101
0-IIb	13 (44.8)	3 (25.0)	2 (28.6)	8 (80.0)
0-IIc	10 (34.5)	6 (50.0)	3 (42.9)	1 (10.0)
0-IIa + IIc/0-IIc + IIa	6 (20.7)	3 (25.0)	2 (28.6)	1 (10.0)
Surface color					0.002
Whitish discoloration	15 (51.7)	2 (16.7)	4 (57.1)	9 (90.0)
Reddish roughness/spontaneous bleeding	14 (48.3)	10 (83.3)	3 (42.9)	1 (10.0)
VS classification					0.999
DL	29 (100.0)	12 (100.0)	7 (100.0)	10 (100.0)
Irregular MVP	26 (89.7)	10 (83.3)	7 (100.0)	9 (90.0)
Irregular MSP	26 (89.7)	9 (75.0)	7 (100.0)	10 (100.0)
Enlarged/absent IP	25 (86.2)	9 (75.0)	7 (100.0)	9 (90.0)

H. pylori: Helicobacter pylori; VS: Vessel plus surface; DL: Demarcation line; MVP: Microvascular pattern; MSP: Microsurface pattern; IP: Intervening part.