Clinical and endoscopic characteristics of early gastric signet ring cell carcinoma based on Helicobacter pylori infection status

Table 1 Baseline and clinical characteristics of patients with early gastric signet ring cell carcinoma based on Helicobacter pylori infection status, n (%)

Variables	Overall	H. pylori-positive	H. pylori-eradicated	H. pylori-uninfected	P value
n = 29	12 (41.4)	7 (24.1)	10 (34.5)
Age, years, mean ± SD	47.55 ± 12.19	45.25 ± 10.26	54.14 ± 8.65	45.7 ± 15.75	0.347
Sex					0.542
Male	7 (24.1)	4 (33.3)	2 (28.6)	1 (10.0)
Female	22 (75.9)	8 (66.7)	5 (71.4)	9 (90.0)
Symptoms					0.398
Abdominal pain	9 (31.0)	4 (33.3)	1 (14.3)	4 (40.0)
Distension	3 (10.3)	2 (16.7)	0	1 (10.0)
Diarrhea/constipation	2 (7.9)	2 (16.7)	0	0
Routine screening	15 (51.7)	4 (33.3)	6 (85.7)	5 (50.0)
Management					0.545
ESD	19 (65.5)	7 (58.3)	6 (85.7)	6 (60.0)
Surgery	10 (34.5)	5 (41.7)	1 (14.3)	4 (40.0)
En bloc resection	29 (100.0)	12 (100.0)	7 (100.0)	10 (100.0)
Complication					0.25
Bleeding	3 (10.3)	3 (25.0)	0	0
Perforation	0	0	0	0
Infection	1 (3.4)	0	0	1 (10.0)
Anastomotic leakage	0	0	0	0
Recurrence	0	0	0	0

H. pylori: Helicobacter pylori; ESD: Endoscopic submucosal dissection.