Preoperative circulating tumor cells as a prognostic indicator in gastric cancer

doi:10.4251/wjgo.v18.i3.115664

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Mar 15, 2026; 18(3): 115664
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.115664

Table 2 Univariate COX analysis of risk factors affecting progression-free survival in gastric cancer patients

Characteristics	β	SE	P value	OR	95%CI
Age	0.204	0.307	0.506	1.227	(0.672-2.240)
Gender	-0.502	0.320	0.871	0.949	(0.507-1.788)
BMI	-0.059	0.044	0.183	0.943	(0.865-1.028)
Tumor size	1.506	0.441	0.001	4.508	(1.898-10.705)
Differentiation of tumor	0.488	0.312	0.118	1.630	(0.884-3.005)
Tumor location	-0.015	0.305	0.961	0.985	(0.542-1.792)
pT	1.576	0.526	0.003	4.837	(1.725-13.564)
pN	1.560	0.526	0.003	4.759	(1.696-13.354)
pM	1.784	0.373	0.000	5.952	(2.863-12.372)
pTNM	1.393	0.414	0.001	4.027	(1.788-9.069)
Perineural invasion	2.796	1.013	0.006	16.375	(2.251-119.36)
Lymphovascular invasion	1.709	0.600	0.004	5.521	(1.704-17.888)
CTCs-positive	0.655	0.320	0.041	1.925	(1.027-3.605)

CTCs: Circulating tumor cells; BMI: Body mass index; pTNM: Pathologic tumour, node, and metastasis; OR: Odds ratio; CI: Confidence interval.

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Citation: Chen QX, Zeng WM, Zhang YB, Cai YC, Lv CB, Sun YQ, Cai LS. Preoperative circulating tumor cells as a prognostic indicator in gastric cancer. World J Gastrointest Oncol 2026; 18(3): 115664
URL: https://www.wjgnet.com/1948-5204/full/v18/i3/115664.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i3.115664

Chen QX, Zeng WM, Zhang YB, Cai YC, Lv CB, Sun YQ, Cai LS. Preoperative circulating tumor cells as a prognostic indicator in gastric cancer. World J Gastrointest Oncol 2026; 18(3): 115664 [DOI: 10.4251/wjgo.v18.i3.115664]

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