Yiqi Wenyang Jiedu prescription promotes disulfidptosis of gastric cancer by reversing senescent cancer-associated fibroblasts

Figure 4 Mechanism study on Yiqi Wenyang Jiedu prescription intervening in disulfidptosis of MKN45 gastric cancer cells. A: Effect of Yiqi Wenyang Jiedu prescription (YWJP) on the expression of SLC7A11 and GLUT1 in MKN45 cells in HAase environment; B: Effect of YWJP on the NADP⁺/NADPH ratio in MKN45 cells in HAase environment; C: Effect of YWJP on the expression of CYFIP1, Rac1, ARP2, and ARP3 in MKN45 cells in HAase environment; D: Effect of YWJP on the disulfide bond level in MKN45 cells in HAase environment; E: Effect of YWJP on PI staining of MKN45 cells. ^aP < 0.05, ^bP < 0.01, NS: Not significant. Error bars represent the standard error of the data. CAF: Cancer-associated fibroblasts; YWJP: Yiqi Wenyang Jiedu prescription; BS: Blank serum.