Copyright: ©Author(s) 2026.
World J Gastrointest Oncol. Mar 15, 2026; 18(3): 113781
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.113781
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.113781
Figure 9 Western blotting of gastric cancer cells for miR-27b-5p and cAMP response element-binding protein zinc finger regulation of signal transducer and activator of transcription 3 pathway-related protein expression.
A: Overexpression or inhibition of miR-27b-5p and cAMP response element-binding protein zinc finger (CREBZF) on protein status of phosphorylated signal transducer and activator of transcription 3 (STAT3), c-myc, B-cell lymphoma 2, survivin, STAT3, CREBZF, cyclin D1, and Bcl-2-associated X protein in AGS cells; B: Overexpression or inhibition of miR-27b-5p and CREBZF on protein status of phosphorylated STAT3, c-myc, B-cell lymphoma 2, survivin, STAT3, CREBZF, cyclin D1, and Bcl-2-associated X protein in NCI-N87 cells. Bcl-2: B-cell lymphoma 2; Bax: Bcl-2-associated X protein; p-STAT3: Phosphorylated signal transducer and activator of transcription 3; CREBZF: cAMP response element-binding protein zinc finger.
- Citation: Ma FC, Zhang GL, Chen GQ, Ling JW, Li YF, Chi BT, Tang YL, Peng W, Chen G, Wei DM, Rong MH, Ge LY. MiR-27b-5p promotes gastric cancer progression by targeting CREBZF to regulate the STAT3 pathway. World J Gastrointest Oncol 2026; 18(3): 113781
- URL: https://www.wjgnet.com/1948-5204/full/v18/i3/113781.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v18.i3.113781