MiR-27b-5p promotes gastric cancer progression by targeting CREBZF to regulate the STAT3 pathway

doi:10.4251/wjgo.v18.i3.113781

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Mar 15, 2026; 18(3): 113781
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.113781

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Figure 5 Effects of miR-27b-5p and cAMP response element-binding protein zinc finger overexpression and inhibition on gastric cancer proliferation. A: MRNA and protein expression of cAMP response element-binding protein zinc finger (CREBZF) after CREBZF interference in AGS cell line; B: MRNA and protein expression of CREBZF after CREBZF interference in NCI-N87 cell line; C: Impact of overexpression or inhibition of miR-27b-5p and CREBZF on proliferation of AGS cell line; D: Impact of overexpression or inhibition of miR-27b-5p and CREBZF on proliferation of NCI-N87 cell line. ^aP < 0.05, and ^bP < 0.01. NC: Negative control; CREBZF: cAMP response element-binding protein zinc finger; OD: Optical density.

Citation: Ma FC, Zhang GL, Chen GQ, Ling JW, Li YF, Chi BT, Tang YL, Peng W, Chen G, Wei DM, Rong MH, Ge LY. MiR-27b-5p promotes gastric cancer progression by targeting CREBZF to regulate the STAT3 pathway. World J Gastrointest Oncol 2026; 18(3): 113781
URL: https://www.wjgnet.com/1948-5204/full/v18/i3/113781.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i3.113781

Ma FC, Zhang GL, Chen GQ, Ling JW, Li YF, Chi BT, Tang YL, Peng W, Chen G, Wei DM, Rong MH, Ge LY. MiR-27b-5p promotes gastric cancer progression by targeting CREBZF to regulate the STAT3 pathway. World J Gastrointest Oncol 2026; 18(3): 113781 [DOI: 10.4251/wjgo.v18.i3.113781]

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