Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a-/- mice

doi:10.4251/wjgo.v18.i2.114161

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2026; 18(2): 114161
Published online Feb 15, 2026. doi: 10.4251/wjgo.v18.i2.114161

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Figure 3 Effects of taurine on gastric intestinal metaplasia organoids. A: Typical growth progression of normal human gastric organoids over 7 days in culture; B-E: Expression levels of gastrointestinal-related markers in patient 1; F-I: Expression levels of gastrointestinal-related marker genes in patient 2; J-M: Expression levels of gastrointestinal-related marker genes in patient 3. ^aP < 0.05 vs normal control (CON); ^bP < 0.01 vs normal CON; ^cP < 0.001 vs normal CON; ^dP < 0.05 vs gastric intestinal metaplasia (GIM) control; ^eP < 0.01 vs GIM CON.

Citation: Liu K, Zhang X, Li FZ, Zheng PY, Mi Y. Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a^-/- mice. World J Gastrointest Oncol 2026; 18(2): 114161
URL: https://www.wjgnet.com/1948-5204/full/v18/i2/114161.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i2.114161

Liu K, Zhang X, Li FZ, Zheng PY, Mi Y. Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a^-/- mice. World J Gastrointest Oncol 2026; 18(2): 114161 [PMID: 41695925 DOI: 10.4251/wjgo.v18.i2.114161]

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