Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a-/- mice

doi:10.4251/wjgo.v18.i2.114161

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2026; 18(2): 114161
Published online Feb 15, 2026. doi: 10.4251/wjgo.v18.i2.114161

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Figure 2 Taurine increases the mucin 5AC (MUC5AC) level and inhibits the expression of caudal type homeobox 2, MUC2, and Trefoil factor family 3 in Atp4a^-/- mice. A: Expression of caudal type homeobox 2 (CDX2), mucin 2 (MUC2), Trefoil factor family 3 (TFF3) and MUC5AC in Atp4a^-/- mouse gastric tissues was assessed via immunohistochemistry (IHC) staining (n = 6); B: IHC scores of CDX2, MUC2, and TFF3 (n = 6); C: IHC score of MUC5AC (n = 6). ^aP < 0.01 vs Atp4a^-/-; ^bP < 0.01 vs wild-type (WT).

Citation: Liu K, Zhang X, Li FZ, Zheng PY, Mi Y. Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a^-/- mice. World J Gastrointest Oncol 2026; 18(2): 114161
URL: https://www.wjgnet.com/1948-5204/full/v18/i2/114161.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i2.114161

Liu K, Zhang X, Li FZ, Zheng PY, Mi Y. Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a^-/- mice. World J Gastrointest Oncol 2026; 18(2): 114161 [PMID: 41695925 DOI: 10.4251/wjgo.v18.i2.114161]

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