Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a-/- mice

doi:10.4251/wjgo.v18.i2.114161

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2026; 18(2): 114161
Published online Feb 15, 2026. doi: 10.4251/wjgo.v18.i2.114161

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Figure 1 Identification of the gastric intestinal metaplasia mouse model and the effects of taurine intervention. A: Hematoxylin and eosin staining of the mouse gastric mucosa (n = 6); B: Alcian blue-periodic acid Schiff staining of the mouse gastric mucosa (n = 6); C: Relative expression levels of gastric intestinal metaplasia-related genes detected by quantitative PCR (qPCR; n = 6); D: Relative expression level of MUC5AC detected by qPCR (n = 6). ^aP < 0.05 vs wild-type (WT); ^bP < 0.01 vs WT; ^cP < 0.05 vs Atp4a^-/-; ^dP < 0.01 vs Atp4a^-/-.

Citation: Liu K, Zhang X, Li FZ, Zheng PY, Mi Y. Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a^-/- mice. World J Gastrointest Oncol 2026; 18(2): 114161
URL: https://www.wjgnet.com/1948-5204/full/v18/i2/114161.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i2.114161

Liu K, Zhang X, Li FZ, Zheng PY, Mi Y. Taurine suppresses gastric intestinal metaplasia in patient-derived organoids and Atp4a^-/- mice. World J Gastrointest Oncol 2026; 18(2): 114161 [PMID: 41695925 DOI: 10.4251/wjgo.v18.i2.114161]

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