Ferroptosis-mitochondria-related molecular subtypes and prognostic signature reveal immune and pathway heterogeneity in hepatocellular carcinoma

Figure 5 External performance evaluation and prognostic assessment of the six-gene risk score. A: Univariate Cox regression analysis in The Cancer Genome Atlas liver hepatocellular carcinoma; B: Multivariable Cox regression analysis adjusted for age, sex, pathological stage, and tumor grade; C: Cox analysis of the continuous risk score across The Cancer Genome Atlas liver hepatocellular carcinoma, GSE14520, and ICGC-LIRI-JP; D: Summary of time-dependent areas under the curve across datasets; E: Kaplan-Meier curve in GSE14520; F: Kaplan-Meier curve in ICGC-LIRI-JP. TCGA-LIHC: The Cancer Genome Atlas liver hepatocellular carcinoma; AUC: Area under the curve; ROC: Receiver operating characteristic; ICGC-LIRI-JP: International Cancer Genome Consortium Liver Cancer-RIKEN Japan.