Ferroptosis-mitochondria-related molecular subtypes and prognostic signature reveal immune and pathway heterogeneity in hepatocellular carcinoma

doi:10.4251/wjgo.124061

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Nov 15, 2026; 18(11): 124061
Published online Nov 15, 2026. doi: 10.4251/wjgo.124061

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Figure 2 Identification of ferroptosis-mitochondria-related molecular subtypes in The Cancer Genome Atlas liver hepatocellular carcinoma. A: Consensus clustering cumulative distribution function curve; B: Delta area plot; C: Consensus matrix for k = 4; D: Heatmap showing the expression patterns of the 47 genes across the four molecular subtypes; E: Kaplan-Meier survival curves comparing overall survival among the four molecular subtypes; F: Distribution of clinical characteristics across the four molecular subtypes. TCGA-LIHC: The Cancer Genome Atlas liver hepatocellular carcinoma; CDF: Cumulative distribution function.

Citation: Han S, Feng ZW, Ran Y, Ma GP, Zhou YC, Lv JZ, Li XB, Wang CH, Wang LZ, Hu SP. Ferroptosis-mitochondria-related molecular subtypes and prognostic signature reveal immune and pathway heterogeneity in hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(11): 124061
URL: https://www.wjgnet.com/1948-5204/full/v18/i11/124061.htm
DOI: https://dx.doi.org/10.4251/wjgo.124061

Han S, Feng ZW, Ran Y, Ma GP, Zhou YC, Lv JZ, Li XB, Wang CH, Wang LZ, Hu SP. Ferroptosis-mitochondria-related molecular subtypes and prognostic signature reveal immune and pathway heterogeneity in hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(11): 124061 [DOI: 10.4251/wjgo.124061]

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