Ferroptosis-mitochondria-related molecular subtypes and prognostic signature reveal immune and pathway heterogeneity in hepatocellular carcinoma

doi:10.4251/wjgo.124061

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Nov 15, 2026; 18(11): 124061
Published online Nov 15, 2026. doi: 10.4251/wjgo.124061

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Figure 1 Identification of ferroptosis-mitochondria-related genes in hepatocellular carcinoma. A: Study workflow; B: Venn diagram showing the overlap between ferroptosis-related and mitochondrial genes; C: Expression heatmap of the 12 significantly differentially expressed ferroptosis-mitochondria-related genes in tumor and normal liver tissues from The Cancer Genome Atlas liver hepatocellular carcinoma cohort; D: Differential expression volcano plot; E: Forest plot of representative survival-associated overlapping genes based on univariate Cox regression. TCGA-LIHC: The Cancer Genome Atlas liver hepatocellular carcinoma.

Citation: Han S, Feng ZW, Ran Y, Ma GP, Zhou YC, Lv JZ, Li XB, Wang CH, Wang LZ, Hu SP. Ferroptosis-mitochondria-related molecular subtypes and prognostic signature reveal immune and pathway heterogeneity in hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(11): 124061
URL: https://www.wjgnet.com/1948-5204/full/v18/i11/124061.htm
DOI: https://dx.doi.org/10.4251/wjgo.124061

Han S, Feng ZW, Ran Y, Ma GP, Zhou YC, Lv JZ, Li XB, Wang CH, Wang LZ, Hu SP. Ferroptosis-mitochondria-related molecular subtypes and prognostic signature reveal immune and pathway heterogeneity in hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(11): 124061 [DOI: 10.4251/wjgo.124061]

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