Prognostic impact of post-chemoradiotherapy muscle quality in non-elderly adults with esophageal squamous cell carcinoma

Table 1 Participant baseline characteristics stratified by survival state

Characteristics	Overall	Survival	Death	P value
Sex				0.851
Female	55 (21.6)	20 (7.8)	35 (13.7)
Male	200 (78.4)	70 (27.5)	130 (51)
Age (year)	63.9 ± 9.4	63.4 ± 7.9	64.1 ± 10.1	0.591
KPS				0.028
70	6 (2.4)	0 (0)	6 (2.4)
80	107 (42)	31 (12.2)	76 (29.8)
90	140 (54.9)	59 (23.1)	81 (31.8)
100	2 (0.8)	0 (0)	2 (0.8)
Smoking history				0.445
No	108 (42.4)	41 (16.1)	67 (26.3)
Yes	147 (57.6)	49 (19.2)	98 (38.4)
Alcohol history				0.091
No	115 (45.1)	47 (18.4)	68 (26.7)
Yes	140 (54.9)	43 (16.9)	97 (38)
Tumor location				0.428
Cervical	8 (3.1)	5 (2)	3 (1.2)
Upper thoracic	53 (20.8)	21 (8.2)	32 (12.5)
Middle thoracic	96 (37.6)	32 (12.5)	64 (25.1)
Lower thoracic	86 (33.7)	29 (11.4)	57 (22.4)
Abdominal	12 (4.7)	3 (1.2)	9 (3.5)
RT dose (Gy)	66 (62, 66)	66 (60, 66)	66 (64, 66)	0.039
Post-TC (mmol/L)	4.48 (3.81, 5.28)	4.91 (4.05, 5.53)	4.22 (3.72, 5.13)	0.002
Post-TG (mmol/L)	1.30 (0.94, 1.66)	1.44 (1.02, 1.79)	1.23 (0.90, 1.53)	0.010
Post-BMI (kg/m2)	21.1 ± 2.7	21.5 ± 2.7	20.9 ± 2.7	0.072
Post-Hb (g/L)	111.63 ± 15.53	112.02 ± 15.84	111.42 ± 15.39	0.475
Post-Alb (g/L)	37.54 ± 7.12	38.11 ± 10.14	37.22 ± 4.73	0.763
T stage				< 0.001
2	28 (11)	22 (8.6)	6 (2.4)
3	114 (44.7)	47 (18.4)	67 (26.3)
4	113 (44.3)	21 (8.2)	92 (36.1)
N stage				0.011
0	6 (2.4)	5 (2)	1 (0.4)
1	79 (31)	29 (11.4)	50 (19.6)
2	118 (46.3)	45 (17.6)	73 (28.6)
3	52 (20.4)	11 (4.3)	41 (16.1)
Clinical stage				0.583
I-III	138 (54.1)	48 (18.8)	90 (35.3)
IV	117 (45.9)	42 (16.5)	75 (29.4)
Post-MYO				0.126
No	58 (22.7)	25 (9.8)	33 (12.9)
Yes	197 (77.3)	65 (25.5)	132 (51.8)
Post-LMM				0.216
No	188 (74)	70 (27.6)	118 (46.5)
Yes	66 (26)	19 (7.5)	47 (18.5)

Categorical variables were presented as n (%). Continuous variables were expressed as mean ± SD or median (interquartile range). KPS: Karnofsky Performance Status; RT: Radiotherapy; Post-TC: Post-treatment total cholesterol; Post-TG: Post-treatment triglyceride; Post-BMI: Post-treatment body mass index; Post-Hb: Post-treatment hemoglobin; Post-Alb: Post-treatment albumin; Post-MYO: Post-treatment myosteatosis; Post-LMM: Post-treatment low muscle mass.