Microbial succession driven by Alistipes depletion shapes the mesenchymal and immune-excluded consensus molecular subtype 4 colorectal cancer landscape

doi:10.4251/wjgo.122507

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Nov 15, 2026; 18(11): 122507
Published online Nov 15, 2026. doi: 10.4251/wjgo.122507

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Figure 3 Differential expression and enrichment analysis. A: Volcano plots of differentially expressed genes between tumor (cancer tissue) and adjacent (cancer-adjacent para-carcinoma) tissues; B: Gene ontology and Kyoto Encyclopedia of Genes and Genomes enrichment of differentially expressed genes; C: Upset plot showing shared enriched pathways across Consensus Molecular Subtypes classifications. CMS: Consensus Molecular Subtypes.

Citation: Hu JD, Qiu CJ, Song ZB, Xia ZW, Wang HT, Geng H. Microbial succession driven by Alistipes depletion shapes the mesenchymal and immune-excluded consensus molecular subtype 4 colorectal cancer landscape. World J Gastrointest Oncol 2026; 18(11): 122507
URL: https://www.wjgnet.com/1948-5204/full/v18/i11/122507.htm
DOI: https://dx.doi.org/10.4251/wjgo.122507

Hu JD, Qiu CJ, Song ZB, Xia ZW, Wang HT, Geng H. Microbial succession driven by Alistipes depletion shapes the mesenchymal and immune-excluded consensus molecular subtype 4 colorectal cancer landscape. World J Gastrointest Oncol 2026; 18(11): 122507 [DOI: 10.4251/wjgo.122507]

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