Proportion of esophageal keratinized area ≥ 30% reduces accuracy of preoperative endoscopic evaluation in early esophageal squamous cell carcinoma

doi:10.4251/wjgo.121634

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Nov 15, 2026; 18(11): 121634
Published online Nov 15, 2026. doi: 10.4251/wjgo.121634

Table 3 Pathological characteristics of early esophageal squamous cell carcinoma with and without esophageal keratosis, n (%)

Variable	Esophageal keratosis (n = 46)	Non-esophageal keratosis (n = 75)	P value
Noninvasive ESCC (65)¹	17 (36.96)	48 (64)	0.004
Invasive ESCCs (56)²	29 (63.04)	27 (36)	0.004

¹Indicates number of cases of high-grade intraepithelial neoplasia and carcinoma in situ.

²Indicates number of cases of intramucosal and submucosal carcinoma.

ESCC: Esophageal squamous cell carcinoma.

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Citation: Zhang YJ, Wen W, Li F, Yuan J, Zou DH, Shi HP, Liang C, Yang Y. Proportion of esophageal keratinized area ≥ 30% reduces accuracy of preoperative endoscopic evaluation in early esophageal squamous cell carcinoma. World J Gastrointest Oncol 2026; 18(11): 121634
URL: https://www.wjgnet.com/1948-5204/full/v18/i11/121634.htm
DOI: https://dx.doi.org/10.4251/wjgo.121634

Zhang YJ, Wen W, Li F, Yuan J, Zou DH, Shi HP, Liang C, Yang Y. Proportion of esophageal keratinized area ≥ 30% reduces accuracy of preoperative endoscopic evaluation in early esophageal squamous cell carcinoma. World J Gastrointest Oncol 2026; 18(11): 121634 [DOI: 10.4251/wjgo.121634]

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