Proportion of esophageal keratinized area ≥ 30% reduces accuracy of preoperative endoscopic evaluation in early esophageal squamous cell carcinoma

doi:10.4251/wjgo.121634

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Nov 15, 2026; 18(11): 121634
Published online Nov 15, 2026. doi: 10.4251/wjgo.121634

Table 2 Endoscopic data for early esophageal squamous cell carcinoma with and without esophageal keratosis, n (%)

Variable		Esophageal keratosis (n = 46)	Nonesophageal keratosis (n = 75)	P value
Morphology	0-IIa	7 (15.22)	11 (14.67)	0.722
	0-IIb	37 (80.43)	58 (77.33)
	0-IIc	2 (4.35)	6 (8)
Location	Upper thoracic esophagus	2 (4.35)	7 (9.33)	0.561
	Middle thoracic esophagus	21 (45.65)	31 (41.33)
	Lower thoracic esophagus	23 (50)	37 (49.34)
Size (cm)	≥ 2	30 (65.22)	40 (53.33)	0.199
Size (cm)	< 2	16 (34.78)	35 (46.67)	0.199

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Citation: Zhang YJ, Wen W, Li F, Yuan J, Zou DH, Shi HP, Liang C, Yang Y. Proportion of esophageal keratinized area ≥ 30% reduces accuracy of preoperative endoscopic evaluation in early esophageal squamous cell carcinoma. World J Gastrointest Oncol 2026; 18(11): 121634
URL: https://www.wjgnet.com/1948-5204/full/v18/i11/121634.htm
DOI: https://dx.doi.org/10.4251/wjgo.121634

Zhang YJ, Wen W, Li F, Yuan J, Zou DH, Shi HP, Liang C, Yang Y. Proportion of esophageal keratinized area ≥ 30% reduces accuracy of preoperative endoscopic evaluation in early esophageal squamous cell carcinoma. World J Gastrointest Oncol 2026; 18(11): 121634 [DOI: 10.4251/wjgo.121634]

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