HMGA2 promotes epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma via transforming growth factor-β/small mothers against decapentaplegic 2

Figure 6 HMGA2 promotes intrahepatic cholangiocarcinoma cell growth in nude mice. A: Images of xenograft tumors and tumor growth curves 3 weeks after implantation; B: Resected tumor tissues and tumor weight analysis; C: Immunohistochemical staining of HMGA2 in xenograft tumors. Original magnification, × 40; scale bar, 300 μm. ^aP < 0.05. ^bP < 0.01. ^cP < 0.001. ^dP < 0.0001. OE-HMGA2: HMGA2 over-expression; sh-HMGA2: Short hairpin RNA-mediated HMGA2 knockdown.