Copyright: ©Author(s) 2026.
World J Gastrointest Oncol. Oct 15, 2026; 18(10): 123758
Published online Oct 15, 2026. doi: 10.4251/wjgo.123758
Published online Oct 15, 2026. doi: 10.4251/wjgo.123758
Table 3 Binary logistic regression analysis of factors associated with positive fecal gene methylation test results
| Factor | β coefficient | SE | Wald χ2 | P value | OR | 95%CI | |
| Lower limit | Upper limit | ||||||
| Smoking | 0.518 | 0.182 | 8.114 | 0.004 | 1.679 | 1.175 | 2.398 |
| Drinking alcohol | 0.399 | 0.175 | 5.221 | 0.022 | 1.491 | 1.058 | 2.100 |
| Pickled foods | 0.603 | 0.174 | 11.969 | 0.001 | 1.827 | 1.299 | 2.570 |
| High-salt diet | 0.954 | 0.179 | 28.483 | 0.000 | 2.596 | 1.829 | 3.685 |
| Excessive consumption of red meat | 0.312 | 0.150 | 4.310 | 0.038 | 1.366 | 1.018 | 1.834 |
| Insufficient dietary fiber | 0.576 | 0.160 | 13.008 | 0.000 | 1.778 | 1.301 | 2.431 |
| Hypertension | 0.873 | 0.169 | 26.656 | 0.000 | 2.393 | 1.718 | 3.333 |
| Diabetes | 1.254 | 0.209 | 35.918 | 0.000 | 3.505 | 2.326 | 5.282 |
| Family history of colorectal cancer | 0.644 | 0.205 | 9.862 | 0.002 | 1.903 | 1.274 | 2.844 |
| HP infection | 0.575 | 0.148 | 15.063 | 0.000 | 1.777 | 1.329 | 2.376 |
| Gender | -0.662 | 0.148 | 19.865 | 0.000 | 0.516 | 0.386 | 0.690 |
| Year (≥ 60 years vs < 60 years) | 0.514 | 0.150 | 11.685 | 0.001 | 1.672 | 1.245 | 2.245 |
- Citation: Chen RY, Zhang DY, Huang YL, Yao JM, Zhong X, Li PP, Bai FH. Application of fecal DNA multi-gene methylation testing in colorectal cancer screening in Haikou City. World J Gastrointest Oncol 2026; 18(10): 123758
- URL: https://www.wjgnet.com/1948-5204/full/v18/i10/123758.htm
- DOI: https://dx.doi.org/10.4251/wjgo.123758