Application of fecal DNA multi-gene methylation testing in colorectal cancer screening in Haikou City

Table 2 Univariate analysis of factors associated with positive fecal gene methylation test results in Haikou City (n = 4050)

Variable	Participants, n	Positive cases, n	χ2 value	P value
Gender			21.860	< 0.01
Male	1733	122
Female	2317	87
Age (years)			30.282	< 0.01
40-49	1453	57
50-59	1363	66
60-69	977	55
70-74	257	31
H. pylori infection			13.672	< 0.01
Yes	1382	96
No	2668	113
Preserved food intake			13.31	< 0.01
Frequent	628	51
Infrequent	3422	158
High-salt diet			37.05	< 0.01
Yes	448	50
No	3602	159
Long-term smoking history			8.658	0.03
Yes	589	45
No	3461	164
Excessive alcohol consumption			6.395	0.011
Yes	707	50
No	3343	159
Hypertension			27.538	< 0.01
Yes	597	57
No	3453	152
Diabetes			38.776	< 0.01
Yes	250	34
No	3800	175
Family history			11.826	< 0.01
Yes	384	34
No	3666	175
Excessive consumption of red meat			5.352	0.021
Yes	2146	127
No	1904	82
Consuming too little dietary fiber			12.173	< 0.01
Yes	2380	147
No	1670	62

H. pylori: Helicobacter pylori.