Marked elevation of alpha fetoprotein caused by hepatoid adenocarcinoma of stomach: A case report

Table 2 Serum alpha-fetoprotein levels and treatment response

Ref.	Initial AFP levels	Treatment and duration	Post-treatment AFP levels
Mahajan et al[19], 2014	6590	Radical gastrectomy, 6 months of chemotherapy: 5-fluorourcil and cisplatin	125
Shen et al[20], 2016	14399	Neoadjuvant therapy with 2 cycles of chemotherapy: Oxaliplatin and capecitabine, followed by gastrectomy and resection of left lobe of liver	10
Yoshizawa et al[26], 2017	1214	Emergency laparotomy with distal gastrectomy, cholecystectomy and reconstruction using Billroth II, followed by chemotherapy with S-1 (tegafur/gimeracil/oteracil)	Normalised (author didn’t specify the value)
Zhang et al[14], 2022	6998	6 cycles of docetaxel, oxaliplatin, tegafur gimeracil, followed by 3 cycles of oteracil potassium capecitabine	Normalised (author didn’t specify the value)
Sun et al[23], 2022	1210	One cycle of chemotherapy: Oxaliplatin and S-1. 11 cycles of sintilimab	0
Zhong et al[25], 2026	919	Billroth II gastrectomy, right hemihepatectomy, adjuvant chemoradiotherapy (capecitabine)	14
Li et al[16], 2024	52951	Neoadjuvant therapy with chemo-immunotherapy: Oxaliplatin, S-1, sintilimab and laparoscopic total gastrectomy with lymph node dissection	9

AFP: Alpha-fetoprotein.