Copyright: ©Author(s) 2026.
World J Gastrointest Oncol. Oct 15, 2026; 18(10): 123542
Published online Oct 15, 2026. doi: 10.4251/wjgo.123542
Published online Oct 15, 2026. doi: 10.4251/wjgo.123542
Table 1 Summary of reported cases on hepatoid adenocarcinoma with their alpha-fetoprotein levels before and after treatment
| Ref. | Age, sex | Gastroscopy findings | AFP pre-treatment (ng/mL) | AFP post-treatment (ng/mL) | Pres-ence of PVT | Treatment | Prognosis (months) |
| Mahajan et al[19], 2014 | 60 male | Ulcerated mass - antrum | 6590 | 125 | - | Chemotherapy | 12 |
| Shen et al[20], 2016 | 70 male | Mass - antrum | 14399 | 10 | - | Chemotherapy, surgery | 7 |
| Quino-Florentin et al[21], 2021 | 44 female | Infiltrative mass - cardia | 49800 | - | - | Chemotherapy | 0 |
| Sun et al[23], 2022 | 60 male | Mass - body | 1210 | 0 | - | Chemotherapy | 8 |
| Zhang et al[14], 2022 | 57 male | Mass - antrum | 6998 | Normal | Yes | Chemotherapy | 12 |
| Bathobakae et al[24], 2024 | 49 female | Ulcerated mass - body | 1252 | - | - | Chemotherapy | 6 |
| Zhu et al[22], 2024 | 80 male | Infiltrative mass - body | 22195 | - | - | Chemotherapy | 0.5 |
| Zhong et al[25], 2026 | 68 male | Mass - antrum | 919 | 8.2 | - | Chemotherapy, surgery | 14 |
| Li et al[16], 2024 | 64 male | Mass - cardia | 52951 | 9 | - | Chemotherapy, immunotherapy, surgery | 6 |
| This case | 75 male | Ulcerated mass - body | 889200 | - | Yes | Chemotherapy, immunotherapy | 0.5 |
- Citation: Sun SY, Elliott T, Johnstone M, Facey M, Chin JK, Gangadharan SK. Marked elevation of alpha fetoprotein caused by hepatoid adenocarcinoma of stomach: A case report. World J Gastrointest Oncol 2026; 18(10): 123542
- URL: https://www.wjgnet.com/1948-5204/full/v18/i10/123542.htm
- DOI: https://dx.doi.org/10.4251/wjgo.123542